Advanced Colon Cancer Treatment in India: What Patients Must Know

03 Dec, 2025

Getting the news of being diagnosed at Stage IV colon cancer can be overwhelming — sometime patients even lose the hope of recovery from treatment. However, today, times have changed. Advanced treatment, better surgical technique, and precise therapy offers real hope. Many patients not only live longer but also maintain an excellent quality of life. With the right approach and the right specialist, even stage IV disease can be controlled, and in selected cases, cured.

This blog brings together clear, easy-to-understand information on advanced colorectal cancer treatment, guided by the clinical approach of Dr. Vivek Mangla, one of Delhi NCR’s leading advanced stage colorectal cancer specialist known for managing complex and metastatic cases.

What Does Stage IV Colon or Colorectal Cancer Mean?

Colon cancer is called Stage IV when the tumour that started in the colon or rectum has spread beyond the intestine to other organs. The most common areas include:

• Liver
• Lungs
• Peritoneum (the lining inside the abdomen)

But “Stage IV” is not a single category, it is divided into:

Stage IV A

Cancer has spread in a limited way to one site — such as a few spots in the liver, lungs, or peritoneum.
➡️These cases often have a significant chance of long-term control or cure.

Stage IV B

Cancer has spread more widely.
➡️Even here, modern chemotherapy, immunotherapy, and targeted therapy can significantly extend survival and keep patients stable.

Modern Treatment Options for Advanced Colon Cancer

Treatment is personalised based on the spread of the disease, the patient’s overall health, and how the tumour responds to medicines.

Chemotherapy, Targeted Therapy & Immunotherapy

These form the foundation of Stage IV treatment.
They help shrink tumours, control spread, and prepare selected patients for surgery.

Advanced Surgery for Liver or Lung Metastasis

If the cancer has spread only to limited areas of the liver or lungs, surgery can remove those spots.

For example:

• During colon surgery, a part of the liver affected by cancer can be removed safely.
• Lung nodules can also be removed in selected patients.

In 30–50% of carefully chosen Stage IV A patients, surgery can offer the possibility of a cure.

Treatment for Peritoneal Spread (Carcinomatosis)

When the cancer spreads to the peritoneum, treatment usually begins with chemotherapy.
If the disease becomes limited and controllable, specialists consider Cytoreductive Surgery (CRS) combined with HIPEC — a technique where heated chemotherapy is delivered inside the abdomen during surgery.

This approach helps achieve long-term disease control in selected patients.

Why Choose an Advanced Colorectal Specialist?

Stage IV colon cancer treatment requires:

• Accurate staging
• Complex treatment planning
• Coordination between medical oncology and surgical oncology
• Experience in surgery for metastasis (liver, lung, peritoneum)
• Skill in CRS + HIPEC procedures

This is where the experience of a colorectal cancer specialist like Dr. Vivek Mangla becomes crucial.

About Dr. Vivek Mangla

Dr. Mangla is a highly experienced colorectal and GI onco-surgeon in Delhi NCR, trained extensively in advanced cancer surgeries including:

• Metastasis removal (liver, lung, peritoneum)
• Cytoreductive surgery
• HIPEC
• Complex colorectal resections

Under his care, many patients with advanced colon cancer have achieved long-term remissions and cure.

If you or your family member has been diagnosed with advanced colorectal cancer, consulting an expert early can make a significant difference in outcomes.

CTA with Patient Testimonials

Most Asked Questions (FAQs) About Advanced Colon Cancer

1. Can stage IV colon cancer be cured?

In selected patients where the spread is limited (Stage IV A), removing the primary tumour and metastatic deposits can lead to long-term cure in 30–50% of cases.

2. How long can patients live with advanced colon cancer?

With modern chemotherapy, targeted therapy, and proper surgical planning, many Stage IV patients live 2.5 years or more, often with good quality of life.

3. Is surgery possible in metastatic colon cancer?

Yes. Liver, lung, and even peritoneal metastases can be removed in carefully chosen patients. Surgery helps improve survival in this scenario.

4. What is HIPEC and when is it used?

HIPEC (Hyperthermic Intraperitoneal Chemotherapy) is used when cancer has spread to the abdominal lining. It is combined with Cytoreductive Surgery to tackle microscopic disease.

5. When should I meet a colorectal cancer specialist?

Immediately after a diagnosis of Stage IV cancer — early specialist involvement helps plan treatment correctly from the beginning.

6. What are the early symptoms of colon cancer?

• Changes in bowel habits
• Unexplained weight loss
• Blood in stool
• Persistent abdominal pain
• Fatigue or low hemoglobin

7. Where can I find an advanced colorectal cancer surgeon in Delhi?

Dr. Vivek Mangla practices in leading hospitals of Delhi-NCR and specialises in advanced colorectal oncology, metastasis surgery, and HIPEC.

Final Word

A Stage IV colorectal cancer diagnosis is not the end of the road. With the right colorectal cancer specialist, advanced therapies, and a structured treatment plan, patients today have more hope and better outcomes than ever before.

If you want to understand your treatment options or need a second opinion, consult Dr. Vivek Mangla, a trusted name in advanced colorectal cancer care in Delhi.